Cardiac Contractility
نویسندگان
چکیده
منابع مشابه
Cardiac work and contractility.
It has been customary to regard the heart as a pump maintaining the flow of blood, and to assess the work done by the heart from the pressure and volume of blood leaving the ventricles. While correct in physical terms, measurement of external cardiac work in this way is a poor index of the myocardial oxygen consumption which is related to the work done by the ventricular muscle. Systolic pressu...
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The heart's physiological performance, unlike that of skeletal muscle, is regulated primarily by variations in the contractile force developed by the individual myocardial fibers. In an attempt to identify the basis for the characteristic properties of myocardial contraction, the individual cardiac contractile proteins and their behavior in contractile models in vitro have been examined. The lo...
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Endothelial cells lining the lumen of blood vessels contain the receptors for many substances that alter the contractile tone of smooth muscle in the walls of the blood vessels. In response to their interaction with the signal substances, the endothelial cells release vasoactive factors that modify the contractile state of the vascular smooth muscle. This study was conducted to determine if end...
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The control of intracellular Na levels has long been known to be a crucial part of the regulation of cardiac contractility and the treatment of heart failure. Cardiac glycosides have been used to improve the symptoms of heart failure since William Withering published trials of a foxglove extract obtained from a gypsy woman in the late 1700’s. The active ingredients, digitalis and digoxin, were ...
متن کاملVasodepressor neurons in medulla alter cardiac contractility and cardiac output.
We injected neuroexcitatory and neuroinhibitory agents into the depressor region of the caudal ventrolateral medulla of anesthetized rabbits and determined the effect on arterial pressure, myocardial contractility, cardiac output, and plasma catecholamines and neuropeptide Y. Brief excitation of the sympathoinhibitory neurons with medullary injection of L-glutamate reduced arterial pressure, pe...
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ژورنال
عنوان ژورنال: Journal of Veterinary Internal Medicine
سال: 1987
ISSN: 0891-6640,1939-1676
DOI: 10.1111/j.1939-1676.1987.tb02014.x